Dermatitis Program

Professor Chris Jackson's group at the University of Sydney has undertaken research on APC in chronic wound healing and inflammatory skin disorders for more than a decade and they have published over 60 relevant scientific papers in high impact journals. The following diagram demonstrates the multiple beneficial therapeutic effects of APC.

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Standard topical treatment for dermatitis is corticosteroids; however, a serious side effect of prolonged use is permanent thinning of skin, which worsens the condition.  In 2020, Professor Jackson's group completed a TR47 in dermatitis mouse study showing it to be as effective as corticosteroids, without the side effects.

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Novapep has developed a topical gel with FDA approved excipients. Professor Jackson will undertake G10 dermatitis/burns studies in 2022.

Annual global sales of corticosteroids for dermatitis are ~$2.5 billion and Novapep is targeting a minimum 30% market share within the first three years of marketing approvals. The global market size for burns treatments is $2 billion and the second degree burns market segment is estimated to be one quarter of the total market.